Dergiler / Ege Tıp Bilimleri Dergisi / 2021 / Cilt: 4 - Sayı: 2

Romatoid Artrit ve Ailevi Akdeniz Ateşinin Birlikteliği: Bir Olgu Sunumu ve Literatürün Gözden Geçirilmesi

Coexistence of Rheumatoid Arthritis and Familial Mediterrean Fever: A Case Report and Review of the Literature

Sayfa
61–64
DOI
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Özet

Familial Mediterranean Fever (FMF) is the most prevalent monogenic autoinflammatory disease with clinical features of recurrent episodes of fever, leukocitosis, serositis, myalgia, erysipelas-like skin lesions, lasting 12-72 hours. Rheumatoid arthritis (RA) is a chronic, symmetrical, inflammatory autoimmune disease that affects small joints, eyes, heart, kidneys, and lungs. The exact mechanisms underlying the coexistence of FMF and RA has not reported previously. Also, so far, only 8 cases of the coexistence of FMF and RA have been reported. In this report we aimed to explain the association between FMF and RA and report one more case of this coexistence.

Abstract

Familial Mediterranean Fever (FMF) is the most prevalent monogenic autoinflammatory disease characterized by clinical featuresof recurrent episodes of fever, leukocitosis, serositis, myalgia, erysipelas-like skin lesions, lasting 12-72 hours. Rheumatoidarthritis (RA) is a chronic, systemic inflammatory disease. The most prominent feature is symmetrical pain and swelling of thehands, wrists, feet, and knees. The exact mechanisms underlying the coexistence of FMF and RA has not been reported previously.So far, only 8 cases of the coexistence of FMF and RA have been reported. In this report, we aimed to explain the associationbetween FMF and RA and report one more case of this coexistence.

Anahtar kelimeler: coexistence, familial mediterranean fever, rheumatoid arthritis