Completion Thyroidectomy in Patients Diagnosed with Papillary Thyroid Cancer: Is There a Predictive Factor for Contralateral Lobe Tumor?

Özet

Objectives: Completion thyroidectomy (CT) is defined as the removal of the residual thyroid tissue in the case of detected malignancyafter lobectomy for an indeterminate or non-diagnostic biopsy. Factors such as tumor diameter, aggressive histology,extrathyroidal spread, and positive surgical margin in papillary thyroid cancer (PTC) constitute CT indications. However, the type ofsurgery is controversial especially in patients with a tumor diameter of 1-4 cm. Determination of predictive factors for contralaterallobe tumors (CLTs) in PTC may be helpful for rough or excessive treatment of patients with this common thyroid pathology.The aim of the present study was to determine the predictive factors and rate of detection of CLTs after CT in patients with papillarythyroid carcinoma after lobectomy.Methods: Medical records of patients who underwent lobectomy with the final histological diagnosis of papillary thyroid carcinomafor the study period 2011 to 2016 were reviewed. Demographic data of the patients, diameter, multicentricity and subtypeof tumor, extrathyroidal spread, and vascular invasion rate were obtained. Patients were divided into 2 groups as final histologicalexamination after CT revealed benign (Group 1) and malignant (Group 2).Results: Data of 49 patients were retrospectively analyzed during the study period. The female-to-male ratio was 33/16. The meanage of the patients was 47.59 (23–77) years. Groups 1 and 2 consisted of 30 and 19 patients, respectively. No significant differencewas found between the two groups regarding demographic data and tumor characteristics.Conclusion: Despite the fact that we have not been detecting any predictive factor in predicting the presence of tumor on thecontralateral lobe in our study, the detection of a tumor on the contralateral lobe is frequent.