Dyslipidemia in Lichen Planus: A Case-control Study

Özet

Objectives: Lichen planus (LP) is a chronic inflammatory disease that affects the skin, mucous membranes, scalp and nails. It hasbeen reported that diabetes mellitus and dyslipidemia prevalence were higher in patients with LP. However, most of these reportswere retrospective, database search, which included patients who were on lipid-lowering drugs. This study aims to conduct a prospective case-control study to investigate the association between LP and dyslipidemia.Methods: This study was conducted on 49 patients with LP (mucosal or cutaneous) and 99 healthy controls. All patients weresubjected to clinical and histological examination, whereas controls were subjected to clinical examination. The variables analyzedwere age, sex, tobacco consumption, hypertension, lipid profiles and fasting blood glucose.Results: Serum levels of triglycerides, total cholesterol and LDL cholesterol were higher in patients with LP. However, there wasno significant difference between patients with LP and controls. No significant differences between LP patients and controls wereobserved with the average age, sex, tobacco consumption and hypertension.Conclusion: This prospective case-control study demonstrated that dyslipidemia was more common among patients with LP.Physicians should be aware of this association and consider screening them for dyslipidemia.