Neonatal Kolestaz ile Başvuran Konjenital Hipofiz Hormon Eksikliği Tanili Yenidoğan Olgusu

A Newborn Presented with Cholestasis and Diagnosed with Congenital Pituitary Hormone Deficiency

Özet

Konjenital hipofiz hormon eksikliği neonatal kolestazin sik olmayan nedenidir. Yenidoğan döneminde klinik bulgulari kolestaz ve hipoglisemidir. Sezeryan ile, 37 haftalik, 3700 gr doğan kiz bebekte postnatal birinci hafta hipoglisemi, 3. haftada kolestaz bulgulari gelişti. Çoklu hipofiz hormon eksikliği saptandi. Büyüme hormonu tedavisi ile kolestaz bulgulari düzeldi. Konjenital hipofiz hormon eksikliği, hipoglisemi ve kolestazi olan yenidoğanlarda ayirici tanida akilda tutulmalidir.

Abstract

An infrequent reason of neonatal cholestasis is congenital pituitary hormone deficiency Clinical manifestations of cholestasis and hypoglycaemia developed in a girl baby born with caesarean section at gestational week 37, with a birth weigh of 3700 g. Hypoglycemia symptoms developed at postnatal first and cholestasis at postnatal third week. Multiple pituitary hormone deficiency was identified. Cholestasis symptoms recovered with growth hormone therapy. Congenital pituitary hormone deficiency should be kept in mind in the newborns with hypoglycemia and cholestasis