Dergiler / Records of Natural Products / 2019 / Cilt: 13 - Sayı: 6

Cephalounei A, a New Cephalotaxus Alkaloid from the Powdered Stems of Cephalotaxus fortune Hook. f

Kang Kang MEI,Guo Kai WANG,He Ping CAI,Zhi Hong LUO

Sayfa
506–511
DOI
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Özet

A new Cephalotaxus alkaloid, namely Cephalounei A (1), was isolated from the stems of Cephalotaxus fortune Hook. f. Their structures were elucidated by spectroscopic and mass-spectrometric analyses, including 1D-, 2DNMR and HRESIMS. The relative and absolute stereochemistry of 1 was determined by a combination of NOESY correlations and electronic circular dichroism (ECD) spectra, respectively. The cytotoxicity of all compounds were evaluated against five cancer cell lines.