Aromatic Compounds from the Marine-Derived Fungus Aspergillus versicolor

Özet

Chemical investigation of the EtOAc extract of a marine-derived fungus Aspergillus versicolor SZW5 led to the isolation of one new compound, named aspeverether A (1), and seven known compounds. The structures were determined by extensive analyses of spectroscopic data (1D and 2D NMR, and HRESIMS). Compounds 1 and 3 possessed an unusual 1,3-dimethoxy-2-vinylbenzene moiety, which is rarely found in nature. Compound 6 showed strong inhibitory effect toward -glucosidase with an IC50 value of 71 M, being more active than the positive acarbose (210 M).