A New ent-Pimarane-Type Diterpenoid Glycoside from Siegesbeckia pubescens

Abstract

A new ent-pimarane-type diterpenoid glucoside, along with eight known same skeleton type were isolated from the ethanol extract of Siegesbeckia pubescens Makino by means of various chromatographic techniques (silica gel, RP-8, Sephadex LH-20, Pre-HPLC). Their structures were elucidated on the basis of spectroscopic analyses and the new one identified as ent-15-methylene-2α,16,19-trihydroxy-pimar-8(14)-ene-19O-β-D-glucopyranoside