Dergiler / Records of Natural Products / 2019 / Cilt: 13 - Sayı: 5

Anti-inflammation C19-diterpenoid Alkaloids from Delphinium giraldii Diels

Yan LIU,Zhiyang LIU,Xinyi WANG,Jing ZHANG,Fangfang LIU,Yunlong CONG

Sayfa
379–384
DOI
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Özet

Two new C19-diterpenoid alkaloids named Delphinium alkaloid A (1) and Delphinium alkaloid B (2) were isolated from the Delphinium (Ranunculaceae). Their structures were elucidated by spectroscopic and mass-spectrometric analyses, including 1D-, 2D-NMR and HR-Q-TOF-MS. Compound 1 showed antiinflammatory activity by regulating the inflammatory reaction induced by LPS in Caco2 cell.