Two New Ecdysteroid Glycosides from the Rhizomes of Silene tatarinowii Regel

Özet

: Two new ecdysteroid glycosides, sileneosides I and J (1 and 2), along with four known ecdysteroids (3– 6) were isolated from the rhizomes of Silene tatarinowii Regel. Their structures were determined based on physicochemical properties and spectroscopic methods. In addition, the cytotoxicity of compounds 1–6 was evaluated in vitro in human SGC790, HCT116, A549, and BEL7404 tumor cell lines. The results showed that compounds 1 and 2 exhibited weak cytotoxicity against SGC790 (IC50 82.58 ± 0.53 μM) and A549 cells (96.62 ± 0.58 μM), respectively