Resolution of Vacuole in Central Serous Chorioretinopathy Following Intravitreal Bevacizumab Injection

Özet

We aimed to present a patient with complete resolution of the vacuole sign, which is a previously defi ned optical coherence tomography (OCT) fi nding of central serous chorioretinopathy (CSC), after injection of intravitreal bevazicumab (IVB). A 38-year old male patient presented with the complaint of decreased vision in the left eye. Fundus examination revealed well-defi ned diffuse serous retinal detachment in the macula of the left eye and the OCT section through that area revealed a serous detachment area, hyper-refl ective fi brinous material accumulation and two vacuolar structures visible as hyporefl ective spaces. In this coexistence of the fi ndings, a recurrent CSC episode accompanied by fi brin accumulation was considered and an IVB injection was performed. One month later, OCT revealed complete resolution of the subretinal fl uid and vacuole sign in addition to irregularities in RPE and the ellipsoid zone. IVB injection may be used as an effective treatment in CSC associated with fi brin accumulation and could have an important role in the resolution of the vacuole sign which consists of fi brin accumulation.