A Facile One Pot Synthesis Of Pyrano[2,3-C]Pyrazole Derivatives Using P-Toluene Sulfonic Acid In Aqueous Media

Abstract

A high yielding and fast method for the synthesis of 1,4-Dihydropyrano[2,3-c] pyrazole via one-pot, three component reaction of an aromatic aldehyde, malonitrile and 3-methyl-1-phenyl-2-pyrazolin-5-one using p-toluene sulfonic acid as a catalyst is described Keywords: p-toluene sulfonic acid, 1,4-dihydropyrano[2,3-c]pyrazole, one-pot.