A Novel And Facile Synthesis of 2 (Cyclohexylamino) 6,7 Dihydro 3 Aryl Benzofuran 4(5h) Ones By One Pot Three Component Reaction

Abstract

A simple and efficient synthesis of 2-(cyclohexylamino)- 6,7-dihydro-3-aryl benzofuran-4(5H)-ones derivatives was achieved via a one-pot three –component reaction of cyclohexylisocyanide, aldehydes, and dimedone or 1,3-cyclohexanedione in DMF for 2 hr with good yields. Keywords: Cyclohexyl isocyanide, dimedone, 1,3- cyclohexanedione, one-pot three component reaction