NAA, Cho, Cr and ml changes in parietal lobe white matter and right putamen in patient with preeclampsia

Abstract

Proton MR spectroscopy (MRS) is powerful and noninvasive chemical analysis and it is widely used in the CNS lesions such as neurodegenerative diseases and brain tumors. MRS permits the in vivo measurement of distinct neurochemicals, which can provide information regarding the cellular composition of various brain lesions. We used proton MRS imaging in patient with preeclampsia to assess the effects of preeclampsia on the brain. We measured metabolites in parietal lobe and putamen using single voxel MR spectroscopy. Spectra were analyzed for the presence of choline (Cho), creatine (Cr), N-acetylaspartate (NAA), and myo-inositol (mI). MRS studies were performed initially and ten days later in preeclamptic woman. The aim of this study was to evaluate maternal basal ganglions and parietal lobe MR spectroscopy changes in preeclamptic patient.