Clinical and histopathological analysis of conjunctival tumors

Osman Melih CEYLAN,Yusuf UYSAL,Fazıl Cüneyt ERDUMAN,Kenan GÜLTEKİN,ALİ HAKAN DURUKAN,Serkan KÖKSAL,FATİH MEHMET MUTLU,GÖKHAN ÖZGE

Özet

Bu çalışmanın amacı Türkiye'de üçüncü basamak bir sağlık merkezinde takip edilen konjonktival tümörlerin klinik ve histopatolojik özelliklerinin değerlendirilmesiydi. Mart 1995 ile Mart 2010 arasında konjonktiva tümörü cerrahi rezeksiyonu uygulanan 164 hasta retrospektif olarak değerlendirildi. Klinik veriler hasta dosyalarından toplanarak elde edildi. Hastaların yaş ve cinsiyetleri ile lezyonun klinik ve histopatolojik özellikleri belirlendi. Çalışmadaki hastalardan 139'u (%84.75) erkek, 25'i (%15.24) kadın idi. Hastaların ortalama yaşı 26.4 (aralık, 4-65) yıl idi. Yüz altmış dört konjonktival lezyondan 115'i (%70.12) nevüs, 12'si (%7.31) kronik inflamasyon, 9'u (%5.48) piyojenik granülom, 6'sı (%3.65) limbal dermoid, 5'i (%3.04) ırksal melanozis, 4'ü (%2.43) benign lenfoid hiperplazi, 3'ü (%1.82) hemanjiyom, 2'si (%1.21) primer kazanılmış melanozis, 2'si (%1.21) inflamatuvar polip, 2'si (%1.21) skuamoz hücreli karsinom, 1'i (%0.6) malign melanom, 1'i (%0.6) hastada skuamoz papillom, 1'i (%0.6) keratoakantoma ve 1'i (%0.6) non-Hodgkin lenfoma olarak belirlendi. Çalışmamızda konjonktivanın en sık gözlenen iyi huylu tümörü nevüs olarak saptanmıştır. Yassı hücreli karsinoma nadir görülen kötü huylu konjonktiva tümörü olmakla birlikte, genç yaş grubunda da karşılaşılabilir.

Abstract

The aim of our study was to analyze the clinicopathologic features of conjunctival tumors followed at a tertiary care hospital in Turkey. One hundred and sixty four patients with surgically excised conjunctival tumors followed between March 1995 and March 2010 were retrospectively reviewed. Clinical data were collected from medical records. Age and gender of patients, and clinical and histopathologic findings of lesions were identified. Of all the patients 139 (84.75%) were male and 25 (15.24%) were female. The mean age of the patients was 26.4 years (range 4 to 65 years). Of the 164 conjunctival lesions, 115 (70.12%) were nevus, 12 (7.31%) were chronic inflammation, 9 (5.48%) were pyogenic granuloma, 6 (3.65%) were limbal dermoid, 5 (3.04%) were racial melanosis, 4 (2.43%) were benign lymphoid hyperplasia, 3 (1.82%) were hemangioma, 2 (1.21%) were primary acquired melanosis, 2 (1.21%) were inflammatory polyp, 2 (1.21%) were squamous cell carcinoma, 1 (0.6%) was malignant melanoma, 1 (0.6%) was squamous papilloma, 1 (0.6%) was keratoacanthoma and 1 (0.6%) was non-Hodgkin lymphoma. In our study, we found that the most common conjunctival benign tumor was nevus. Although squamous cell carcinoma is a rare conjunctival malignant tumor, it may be encountered in young age population.