Rinoserebral mukormikoz: Bir olgu sunumu

Özet

Rinoserebral mukormikoz nadir ancak sıklıkla ölümcül seyreden, invaziv bir fungal infeksiyondur. Sıklıkla diabetes mellitus, AİDS, yüksek doz kemoterapi alan hematolojik mâlignîteli ve transplantasyon hastaları gibi immunkompromize konaklarda karşımıza çıkmaktadır. Rinoserebral tutulum en sık görülen formdur. Baş ağrısı, göz çevresinde ağrı, burun kenarında siyah lezyon, dudaklarda ve yüzde şişlik yakınmalarıyla başvuran elli yaşında bayan hastaya, fizik muayene, radyolojik görüntüleme ve histopatolojik bulgularla rinoserebral mukormikoz tanısı'konmuştur. Tekrarlanan cerrahi debridmanlar ve yüksek doz antifungal tedaviye rağmen kaybedilen hasta, son derece mortal seyreden rinoserebral mukormikoz olgularına dikkati çekmek amacıyla sunulmuştur.

Abstract

Rhinocerebral mucormycosis is a rare and potentially life-threatening invasive fungal infection which results in high mortality. It is most often found in patients with diabetes mellitus, in patients with leukemia who have been neutropenic for long periods and who have been receiving broad-spectrum antibacterial drugs. Rhinocerebral mucormycosis is the most common form. A 50-year-old woman was admitted to our hospital because of headache, periorbital pain, a necrotic lesion at nares, swelling of the lips and face. Rhinocerebral mucormycosis was diagnosed with physical and radiologic examinations and histopathologic findings. Although the patient was given an antifungal therapy and debrided surgically repeated times, she didn't improve and died. This case was reported to emphasize the rhinocerebral mucormycosis which results in high mortality.