Clinicopathologic Results in Meniere Disease: Evaluation of 80 patients

Özet

Introduction: Meniere's disease is the second most common disease among peripheral vestibular diseases. However, clinicopathology and treatment of Meniere's disease are not yet fully understood. In this study we aimed to investigate the relationship between the demographic features, audiological findings and treatment modalities of the Meniere's disease. Methods: Demographic characteristics, additional diseases, pure audio audiometric test results and treatment modalities of 80 patients with Meniere's disease were compared retrospectively with statistical methods. Results: The study involved 54 (67.5%) female, and 26 (32.5%) male patients with an average age of 47.5±12.0.54. Right ear was affected in 31 (38.8%) patients, left ear in 38 (47.5%) patients, and both ears in 11 (13.8%) patients. The most common comorbid diseases were diabetes mellitus (n=11) and hypothyroidism (n=11). The average hearing threshold values of 250- 1000 Hz were 35.5±27.4 dBHL for the right ear, 41.4±30.5 dBHL for the left ear. The average threshold values of 2000-8000 Hz were 36.9±29.6 dBHL for the right ear and 45.7±31.4 dBHL for the left ear. There was no statistically significant difference between low and high frequencies in right and left ear (p=0.84, p=0.073). To fix vertigo 35 (43.8%) patients received medical treatment, 17 (21.2%) patients treated with transtympanic steroid ablation, and 28 (35.0%) patients treated with transtympanic gentamycin ablation. Discussion and Conclusion: The prolongation of diagnosis time in Meniere's disease induces additional impairment of highfrequency hearing and also causes difficulties in the diagnosis.