Dergiler / ENT Updates / 2017 / Cilt: 7 - Sayı: 3
Evaluation of olfactory functions in patients with laryngopharyngeal reflux
- Dergi
- ENT Updates
- Sayfa
- 144–148
- DOI
- —
Özet
Larengofarengeal reflü hastalar>nda koku fonksiyonlar>n>n de¤erlendirilmesi Amaç: Çal>flman>n amac> larengofarengeal reflü hastalar>nda koku fonksiyonlar>n> de¤erlendirmektir. Yöntem: Çal>flma, kontrol ve reflü grubu olmak üzere 2 gruptan oluflmaktayd>. Her grupta 50'fler hasta mevcuttu. Reflü grubuna reflü tan>s> koyarken reflü semptom indeksi ve reflü bulgu skorlamas>ndan faydalan>ld>. Bu 2 gruba Connecticut Chemosensory Clinical Research Center (CCCRC) koku testi uygulan>p sonuçlar karfl>laflt>r>ld>. Bulgular: Gruplar>n demografik özelliklerine bak>ld>¤>nda cinsiyet ve sigara kullan>m> oranlar> aç>s>ndan istatistiksel fark bulunmazken yafl de¤iflkeni aç>s>ndan istatistiksel fark vard>. Yafl de¤iflkeninin etkisini ortadan kald>rmak için kovaryans analizi yap>ld>. Kovaryans analizi sonras> hesaplanan ortalama skorlar karfl>laflt>r>ld>. CCCRC testinin en yüksek skorunun 7 oldu¤u bilinmektedir. Buna göre kontrol grubunda CCCRC skoru 5.84±0.13 iken reflü grubunda 5.20±0.11 olarak hesapland>. ndaki bu fark istatistiksel olarak anlaml> idi (p ¤> koku fonksiyonlar>nda total kayba yol açmadan koku fonksiyonlar> üzerinde negatif etkisi bulunmaktad>r.
Abstract
Objective: To evaluate olfactory functions in patients with laryngopharyngeal reflux. Methods: The study consisted of control and reflux groups. Each group consisted of 50 patients. Reflux group received the diagnosis of reflux based on reflux symptom index, and reflux symptom scores. The olfactory test of Connecticut Chemosensory Clinical Research Center (CCCRC) was conducted on these 2 groups, and the results were compared. Results: No statistically significant difference was found between the demographic characteristics such as gender and smoking rates while there was statistically significant difference between the groups in terms of age variable. The covariance analysis was used to eliminate the effect of age variable. The mean scores calculated after covariance analysis were compared. It is known that the higher score of CCCRC test is 7 points. Accordingly, CCCRC scores of the control and reflux groups were 5.84± 0.13, and 5.20±0.11, respectively. This difference between two groups was statistically significant (p<0.001). Conclusion: Laryngopharyngeal reflux disease has a negative effect on olfactory functions without total loss in olfactory functions.