How Much Do Routine Blood Tests Tell Us About Patent Ductus Arteriosus? Is the Red Cell Distribution Width to Platelet Count Ratio or/and Any Platelet Parameter Useful?

Özet

Objectives: In this observational study, to determine whether there is any association between red cell distribution width (RDW)/platelet count ratio (RPR) and hemodynamically significant patent ductus arteriosus (hsPDA) in preterms. Materials and Methods: A total of 233 preterm infants, gestational age <34 weeks were analyzed in the study. Complete blood counts obtained at 24th h, 48th h, 72nd h and 7th days were evaluated for RDW, RPR, platelet parameters and compared for PDA status. Results: Our study included 64 infants with hsPDA and 64 controls. The RDW at 48th h, 72nd h, and 7th day and the RPR at 24th h, 48th h, 72nd h and 7th day were significantly higher in the study compared to the control group; the PCT was lower. The RPR afforded 72.3-79.2% sensitivity and 82.3-89.2% specificity when used to predict hsPDA. Conclusion: None of platelet count, PDW, mean platelet volume, or Platelet Mass index can be used to predict either hsPDA or treatment success, but a low PCT, and a high RDW and RPR, predict hsPDA but not treatment success.