Are Atrial High-rate Episodes a Kind of Sympathetic Overactivity in Patient with Permanent Pacemaker?

Özet

Objectives: Atrial high-rate episodes (AHREs) are important cardiac conditions. The purpose of the trial was to assess sympatho-vagal interaction as evaluated by the heart rate variability (HRV) of holter recordings in patients with AHRE. Materials and Methods: All subjects with cardiac devices including dual chamber permanent pacemakers, attending the outpatient pacemaker control units were included. Transthoracic echocardiography and a rest electrocardiogram, and 24-hour Holter monitoring were performed to all patients. Results: One-hundred and fifty subjects were included in this trial. There were 44 patients (29.3%) with AHRE and 106 subjects (70.7%) without AHRE in all population. Standard deviation of all N-N intervals for a selected time period (102.1±30.5 vs 124.0±50.2; p=0.008) and normalized power in high-frequency band (9.4±6.6, 12.7±7.1; p=0.006) were significantly decreased; however, normalized power in low-frequency band (28.5±12.5, 23.8±11.6; p=0.006) and LF/HF ratio (4.71±3.60, 2.63±1.65; p<0.001) were significantly increased in AHRE patients. Conclusion: There was a sympathetic overactivity in patients with AHRE. Further studies are needed to demonstrate the role of HRV parameters in AHRE patients.