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Manipur is one of the northeastern states of India, comprising of both tribal and non-tribal population groups. Kom (tribal) and Meitei (non-tribal) population groups are considered for the present study. This study examines the socio-demographic correlates of prenatal and post natal deaths among Koms and Meiteis of Manipur. Meiteis are found to have comparatively better socio-economic condition than that of Koms. Two socio-demographic variables have emerged to influence offspring mortality among Meiteis and Koms. While among Meiteis higher socio-economic status is found to significantly reduce offspring mortality, among Koms it is the higher inbreeding which is found to significantly increase the offspring mortality.