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Sida acuta is a weed in agriculture crops. It reduces crop production. Weed control is important in crops management to maintain its vigor and productivity. The increasing threat of herbicide resistance and negative impact of herbicides on environment provides an opportunity for the development of biological agent for weed management. The current work was undertaken to isolate, identify and characterize potential deleterious rhizospheric bacteria from weed species. Rhizospheric bacterial isolates that inhibit weeds, but not crops, will have a potential to develop an effective bacteria based weed management control method for ecologically based weed management systems.