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The aim of this study is to determine the effect of computer assisted instruction on fourth grade primary students’ achievements and their attitudes towards science and technology lesson. In this study, quasi-experimental design was utilized. There were two groups consisting of totally 55 fourth grade primary students who were selected with convenient sampling method from Korfez district of Kocaeli in Turkey. One of the groups was experimental group and the other was control group. The experimental group was taught using the computer asisted instruction based on constructivist approach and the control group was taught using constructivist approach currently used in primary education curriculum of Turkish Education System. The data were collected by means of attitude scale towards science and technology lesson (ASTSTL) and achievement test (AT). The data were analyzed using SPSS statistical packet program. The findings indicated that in terms of both achievment test and attitude scale there was a statistically significiant difference between the post test scores of the groups in favor of experimental group.