European Regional Development Funds, following its establishment in 1974, functioned to create a similarity among member states’ policies, which were demanded to be put into practice in EU pre accession process. Turkish administrative structures are highly centralized. So, in spite of regional policies, especially related to development, being on the agenda in Turkey during certain eras, any institutional progress was not recorded. In 1990’s, centralized administrative structures were under pressure of newly emerged economic and political conditions. Not only had the search of novelty by local level and private sector but also EU pre accession process necessitated the creation of Regional Development Agencies in 2006. This essay mainly focuses on the genesis of Regional Development Agencies by considering domestic and EU influence and try to shed light on the possible future of agencies.